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Week 5 of the college football season delivers one of the most loaded slates yet, and today’s simulations from MyGameSim point to a mix of heavyweight battles and potential upsets. While Vegas has its say on the lines, GameSim sees several games breaking in surprising directions.

We’re two games into the 2025 college football season, and the playoff picture is already shifting fast. The expanded 12-team College Football Playoff means more spots, more jockeying, and more opportunity. The latest odds bring clarity. They spotlight who’s rising, who’s holding steady, and who’s slipping.

Whether you are a college football fan, an NFL enthusiast, a fantasy football player, or a mix of all three, you will likely read a lot of content based on analysis and predictions for the new campaigns ahead. You will, of course, be familiar with the type of content we mean: Win-loss predictions articles for the season, player projections, new season power rankings, and so on.

The University of Illinois Fighting Illini are entering their 2025 football season with more anticipation than ever before. The spotlight falls directly on Memorial Stadium on August 29, when Illinois takes on Western Illinois in their opening matchup.

Ole Miss enters the new season with rising anticipation and plenty of moving parts. After quarterback Austin Simmons made waves in recruiting conversations, fans and analysts alike are eager to see if he’ll deliver on the promise. However, this season, his potential won’t only be based on adapting quickly to the Rebels’ fast-paced culture, but also NIL deals shifting college football’s landscape and talent pipelines widening.